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Blueys 64

Australia
2 Posts

Posted - 09/20/2013 :  21:42:41  Show Profile  Reply with Quote
Hi from Australia.

I am on day four of the Picato treatment.

Did my forehead, which is now very red, with lots of dry tight skin.

Just a waiting game now I guess as to what will follow.

Do I just let it do it's own thing and slowly shed the dead skin or do I use some form of cream to keep it moist.

Man those tubes are small, used a small pair of pliars to squeeze every last drop of the gel out.

We have a very good health system here in Australia, a three tube course of Picato 0.015% cost me the princely sum of $5.90.

Once my forehead clears up I will be doing my cheeks. The ones on my face of course!

Interested in any comments about my progress.
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Dave2001

USA
19 Posts

Posted - 09/23/2013 :  17:08:31  Show Profile  Reply with Quote
It is interesting to hear different experiences.
After few doctors in the US didn't vauch for Picato, I decided for Australian remedy Curaderm and month+ later everything looks very good with few AKs and one BCC. The statistics of Picato's reccurence results put me off, although I would be happy to pay even full price and be ready in 3 days.
All the best with cure and keep posting.
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Blueys 64

Australia
2 Posts

Posted - 09/24/2013 :  14:52:50  Show Profile  Reply with Quote
Just recapping.

Started my three day treatment nine days ago, all going well.

Day one, slight burning sensation and redness on forehead after a few hours, left on for eight hours then lightly washed off with water only.

Day two, more slight burning, redness increased forehead tighter, left on for eight hours then washed off as above.

Day three, less burning feeling, still red tight skin on forehead and starting to scale.

Day four, no pain and scaling of skin makes my forehead feel like a crocodile skin (must be working)

Day five, starting to itch but determined to keep my fingers away.

Day six, getting dry and scaly, directions say not to put anything on it until healed. (alright for them to say)

Day seven, as above.

Day eight, Enough is enough! put lashings of moisturiser on to prevent cracking. Really worked.

Day nine, I feel like the butterfly that has just come into the world.

With a wet cloth in warm water I was able to successfully debraid all the dead skin from my forehead leaving the new skin nice and smooth, albeit still a little red, which is to be expected.

Another week or two and I will be a happy camper.
I will do my cheeks in a months time.
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Ray41

USA
1 Posts

Posted - 09/26/2013 :  09:16:12  Show Profile  Reply with Quote
Did anyone use Aloe after the completion of there three day Picato treatment? I have been using aquafor, but I think the Aloe would feel refreshing after this blowtorch treatment. Thank you in advance for your reply. I am getting close to the completion of my third day application.

Thanks,
Ray
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reelchip

USA
0 Posts

Posted - 10/11/2013 :  10:04:49  Show Profile  Reply with Quote
quote:
Originally posted by Sibo10

My experience with my first treatment with Picato on my scalp was intense pain, burning, intense attacks of goose-pimples (which was very painful when the skin on the scalp contracted). The reaction may depend on the level of the keratosis. In January I had 3 positive tumors surgically removed (thankfully small ones).
I was told not to use any creams or salves to reduce the reaction/pain as it is not yet known if they can 'negate' the process of Picato. So, grin and bear it (grimace and bear it?). It also states clearly that the treated area should not be covered. We suspect the active ingredient is UV sensitive; it needs light to function.
My second treatment starts on Friday and I am a 'bit' nervous.
(An interesting aside; here in Germany the treatment without insurance costs Ç150,00 - $200,00, so at $600 you are (again) being scammed by your drug companies )

It's interesting to see how many are getting different advice from their skin doctors. In the instruction is specifically says that the COMPLETE treatment of three tubes should be used, (one per 24 hours). And the dermatologist who prescribed three tubes for the whole face obviously has no idea what he is doing. The treatment is for 4 sq inches (25 sq cm).

I've attached images of my treatment, after 1 day, 2 days, 3 days, 8 days and 15 days.

Picato after 1 day:

42.41áKB



Picato after 2 days:

32.47áKB



Picato after 3 days:

32.23áKB



Picato after 8 days:

24áKB



Picato after 15 days:

36.39áKB

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lady diana

USA
0 Posts

Posted - 10/17/2013 :  16:06:06  Show Profile  Reply with Quote
I am going to start using Picato 0.015% at the end of the month. At no place in the literature doe it say when to wash your face each day. It will be for pre-cancer of my nose, around my lips and cheeks. Doesn't sound like "fun". How many hours are recommended to wait before washing, and what type of product do you use? Any other info would be great to learn.
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Emy

1 Posts

Posted - 11/21/2013 :  10:21:27  Show Profile  Reply with Quote
quote:
Originally posted by lady diana

I am going to start using Picato 0.015% at the end of the month. At no place in the literature doe it say when to wash your face each day. It will be for pre-cancer of my nose, around my lips and cheeks. Doesn't sound like "fun". How many hours are recommended to wait before washing, and what type of product do you use? Any other info would be great to learn.

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Emy

1 Posts

Posted - 11/21/2013 :  10:33:28  Show Profile  Reply with Quote
I was putting it on at night and not washing it off until the next evening. I want to get the full effect. I put it on half of my nose and the next day, I had a swollen nose, very red and no significant spots. The second morning, I had several small blisters. The third morning, I had another blister and a couple of them were oozing, turned into small scabs that took up to a week to peel off. This was a very mild reaction compared to effudex I did 4 years ago on my entire face. My entire nose was a nasty thick scab for a week or more. And it does prove that you have to keep at it because more damaged skin will continually show up as you age.

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jimb630

USA
4 Posts

Posted - 01/05/2014 :  11:56:44  Show Profile  Reply with Quote
I read this forum prior to beginning my Picato treatment and found it quite helpful. I thought I would return the favor by sharing my experience. Background: I a 65-year-old male diagnosed with actinic keratoses on my forehead and temples. My dermatologist said it was not a real bad case. Mostly I have very tiny, hard dry bumps all over my forehead. They are barely visible, but I notice them every time I wash my face. I also have a couple patches just about eye level on my temples just outside of my eyes. So, here are notes I made over the last 5 days.
Day 1 (1-1-13): 11:30am - It was a little difficult to cover the entire area and a small spot on my ear. There was a very minor burning sensation with the first application. The gel dries very fast. 8:30pm - My forehead feels a little dry. I have been hesitant to touch it, let alone rub it or scratch it, all day. 11:00pm - My head feels a little itchy, but so far so good.
Day 2: 9:00am - My forehead feels a little irritated today. I noticed when I pulled a sweatshirt over my head. I had one small crusty area near one eyebrow. 11:30am - Applied the second treatment. Thanks to a suggestion on this forum, I used a pair of pliers to get every bit of gel from the tube. Great idea! There was just a tiny bit of burning with the application. I am not real raw anywhere at this time. 12:30pm - My head is beginning to feel more irritated and a little more itchy. 5:30pm - My forehead has become red. It does not feel warm like a sunburn, but it hurts like one. My skin feels very tight, and wrinkling my forehead hurts.
Day 3: 8:00am - I was more uncomfortable last night. I did not sleep well. I am a side sleeper, and that irritated my face. I feel very irritated this morning; my skin is itchy, tight and dry. I have some peeling in a couple small areas. 11:30am - Applied my third, and last, application after showering. I could not use a washcloth on my forehead in the shower as my skin felt raw. There was an uncomfortable burning when applying the gel today. 7:30pm - I am feeling more uncomfortable this evening. The tiniest wrinkling of my forehead hurts. It is not unbearable, just very uncomfortable. I had one small spot that oozed last night, but today it is just very sore and getting scaly.
Day 4: 10:00am - I am still quite tender today. I feel as though I was heavily scrubbed with a very stiff brush. My entire forehead is tight and crusty, but it does not look bad. Yesterday it hurt to wear my glasses, but that is OK today. 12:00pm - My shower was the most painful of all days so far. Even lukewarm water just running down my forehead hurt.
Day 5: 6:00am - Last night, the night of Day 4, was my worst. I had a lot more pain. It is just raw. The covering of flakiness is really a hard crust. Anytime I would move and my face or temples would rub the pillow, that hard layer of crust would press into the raw skin beneath it. I did not get much sleep. I have a few very small areas that looked like there was a little bleeding. It is more itchy today. 1:00pm - I showered this morning, and it was painful. I did let some cool water run off my head and down my face, and that felt kind of good. I am still very uncomfortable. It is both itchy and painfully raw at the same time. I feel as though today is the turning point. I feel like the itching is going to overtake the raw pain.

Overall, I guess it has not been as bad as I thought it might be. However, it is not something I would like to go through again. Hopefully, I will be well into healing later this week.
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cpboucher1

USA
1 Posts

Posted - 01/07/2014 :  16:26:49  Show Profile  Reply with Quote
Why can't you apply Picato after a shower? I just showered, how long do I have to wait before I can apply the gel?
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jimb630

USA
4 Posts

Posted - 01/09/2014 :  12:31:06  Show Profile  Reply with Quote
I can't give you a definitive answer, but I assume it has to do with diluting it. Interestingly, my doc told me to apply it after showering, but not to a wet skin. He said some dampness would help it to spread easier. I applied mine about half-an-hour after showering. It worked just fine. Good luck.
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butkus22

USA
6 Posts

Posted - 01/10/2014 :  10:32:35  Show Profile  Reply with Quote
I am a 55 yr. old, blonde hair, blue eyed female with a history of SLE and melanoma. I see a Derm. Oncologist. Skin damage due to excessive sun abuse as a teenager with no screens. Started my first series,1-5-14, which is my whole face and the MD ordered the the higher dosage 0.05%. As you can imagine I look like a gargoyle! Excessive swelling, (eyes almost swollen shut), ulcers, blisters, oozing, etc, I have continued with cold compresses on eyes, and have to compress around mouth and chin because it is so dried and blistered, and cannot eat unless it's soup or everything cut up small. Sleeping is rough, especially since the healing process has begun in various areas and scabbing and itching is a problem. Unfortunately my specialist's last day was the day I saw her, and will meet my new Doc in Feb., so I am working with a resident, as a nurse which is sometimes not a good thing and a ton of questions that were not answered but timing was essential because I am scheduled for a minor procedure next month and need my face to be healed. With all that being said is Aquaphor the way to go and can I start using it now? Category 4+ in severity with all skin reactions, which I am sure is related to the dosage and my autoimmune disease. I need some relief with this dryness so I can get some sleep. Who better to talk to then my fellow patients that are going through this as well. Hopefully this will be the worst. I start my arms in Feb, and chest in March. Better look like a Rockstar when I am done, lol. No seriously, just want all this precancerous crap off my body. Thanks to all !
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jimb630

USA
4 Posts

Posted - 01/10/2014 :  13:29:47  Show Profile  Reply with Quote
Butkus22,

Sounds like you are having it pretty rough. I feel bad about even complaining at all compared to what you are going through. Did you get a call from someone at Leo Pharm after you filled your prescription? A nurse called and emailed me. She said I could call her at any time with concerns and questions. I took advantage and called about using a moisturizer. She told me it was best not to use anything for two weeks. However, she also told me that if I was in real bad shape (which I was not), that I should call my doc and talk to them about getting something.

Hope this helps,
Jim
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butkus22

USA
6 Posts

Posted - 01/10/2014 :  14:23:25  Show Profile  Reply with Quote
Thanks Jim. Resident is nice but hopeless, won't see new specialist until Feb.3rd. I am going to start the Aquaphor. My husband is picking some up. Can't get any worse. I need sleep or I will be on a most wanted poster. My chin is so ulcerated and scabby that it is starting to bleed. Just need to soften some of this stuff. I can handle the forehead and swollen face...just need to get some kind of moisture. Keep drinking lots of water, Hope all goes well with you.
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busybeetrio

USA
1 Posts

Posted - 01/26/2014 :  12:47:02  Show Profile  Reply with Quote
I started Picato on Thursday, Jan 23rd. I woke in the morning with reddish spots one of which was larger and raised. I added the second application on the 24th and the next morning I had blisters on one spot and dark red/scabbed spots on the other two which kinda spread up my neck. Today the blisters burst and now they are burning/tender to anything touching them. Which spots are the true cancer? The blistered spots or the red/scabbed spots? Will this continue to go up my neck to other spots that I did not treat? Also, can I put any cream on my spots or simply let them breath? My spots are on my chest.
1st picture is next morning after 1st nightly treatment
2nd picture is day two after second application

Image Insert:

39.84 KB

Image Insert:

44.78 KB
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butkus22

USA
6 Posts

Posted - 01/27/2014 :  08:26:34  Show Profile  Reply with Quote
Tiny1917, I found that having my Doc write a script specific doage for 90 day thru my mailorder was the cheapest. I have to use a ton. My first treatment was my whole face, which I used 5 tubes. I blistered so bad, I had to back off. My chest is in Feb., R arm in March, Left arm in April. I see MD on Feb. 3rd. We will calculate how much I will need. She will have to write starting date x 3 days, once a day and approx. how many boxes I will need per month per treatment area. If the script is written correctly it will cost me $90.00 all total for co-pay instead of thousands. I wanted to do the 3 day treatment to get it done and over with, but I have to say, the face was brutal. Good Luck.
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butkus22

USA
6 Posts

Posted - 01/27/2014 :  08:41:43  Show Profile  Reply with Quote
Busybeetrio, this was trial and error for me as well if you have read my previous post. Speaking with my 2 pharmacist neighbors, since I didn't get too much info from the resident I was working with ,(will meet my new oncologist on Feb. 3rd), the application is best put on in the afternoon. Needs to absorb and is not to be put on after a shower, because of vasodialation. (Pores open too much because of heat). If you put it on at night and went to bed, chances are it spread to other areas that didn't need treatment. Picato is used for all precancerous skin and it is used as proactive treatment to prevent melanoma and basal cell CA. I have been blessed with 3, my worst, stage 3 on my thigh. They told me if there are blisters and oozing, not to put the ointment directly on that spot. My face was so bad I won't post the pics because I don't think anyone would use this med if they would see it. My treatments were on a Sunday thru Tues. and by Friday my face was so swollen, blistered , oozing and couldn't open my eyes. Thanks to this forum, I did start on the Aquaphor which adds moisture but still allows air to heal. In 2 days I felt much better. I did use cool compresses as well on the blisters and tried to wash the areas with Cefadil and re-apply the Auaphor a couple of times a day. Can hardly wait to start my chest area in the middle of February. Good Luck.
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kdante

USA
1 Posts

Posted - 02/22/2014 :  09:35:55  Show Profile  Reply with Quote
I am on day 10 after first application on face. I had pretty severe reaction, feeling much better now (smooth, no scabs, no pain, slight itch). Although, face is still VERY red and blotchy. I am very concerned about scarring. How long does it take for all the redness to completely heal? I haven't seen much improvement in the past 3 days.
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butkus22

USA
6 Posts

Posted - 02/22/2014 :  10:01:10  Show Profile  Reply with Quote
kdante, my reaction was so severe, they switched me to Flouracil for my chest. Started that Monday. 2 weeks every night. Nothing really happening yet. As far as the Picato, as bad as I was there is no scarring. Kept using the Aquaphor. Did the Picato the beginning of January and still notice some redness after I shower or work out. Since I had such a major reaction, Md's decided to hold off on me doing my arms and see how I react with the Flouracil for now. They did tell me to apply major suncreen to my face, at least a 50, and want me to get an acid peel. Good luck. Picato is wicked.
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cbeaty

USA
1 Posts

Posted - 03/05/2014 :  20:03:29  Show Profile  Reply with Quote
Hello all. I am on Day #4 of the Picato 'experience'. I used it the first day and thought there was something wrong considering what I thought was an extreme reaction so I did not use it the second day and then I read on these forums about how painful it can be and all the redness (feels like looking into an open oven with an extreme sun burn) and that my reaction was somewhat of a typical reaction so I went ahead with days #2 & #3.
My face is super red and there is some peeling and crusting as of this writing. The pain is over with (thank god!). I do fear that perhaps I spread it around too much (2in x 2in being the suggested treatment area). I have been putting on moisturizer (Aquaphor) and have used a little bit of cortisone cream at times. I will say, I do not know if I want to go through Picato again. It was rough stuff. Especially day # 3, I was pacing around trying to distract myself from the pain for the last two hours. I don't see how anyone could put it on before bed or even go to work. It is best to be at home and have your mind set on trying to be as calm as you can and go through the treatment.
In any case, I hope it will work. I am unsure of the results so far.
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angbat

USA
2 Posts

Posted - 03/23/2014 :  10:29:55  Show Profile  Reply with Quote
I picked up my Picato gel prescription yesterday. With my insurance and the $200 copay card from the manufacturer, my copay was $124.00. In the afternoon, I applied it liberally to 2 spots, one on my cheek and the other above my lip. It burned almost the whole time it was on. I am almost positive that I applied too much and did not do a good job avoiding the surrounding areas. So, the surrounding healthy skin areas have huge blisters and swelling and I look like a freak. It feels like a sunburn. Today, I applied it very conservatively just to the treatment areas. I am considering contacting my doctor tomorrow as my reaction is described as "severe" in the patient leaflet. I am also concerned that I may have caused damage to the healthy skin. Any thoughts?
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butkus22

USA
6 Posts

Posted - 03/23/2014 :  11:27:00  Show Profile  Reply with Quote
angbat...I used the gel over my entire face for 3 days, and I would think I had some healthy skin that was involved. There was no damage to the healthy tissue. To be honest, I think I had better results when they switched me to the Efudex on my chest for the 2 week treatment time. Can definitely tell a difference with my chest. Face, I am not sure. See oncologist again next month. They keep trying to push me to get a "blue peel", by Dr. Obagi, who is out of Pittsburgh but nationally known. I don't think it is medically nec. and if you all would see the pics of my face when I went thru the Picato, it looks like I did go thru a major acid peel. The docs and residents that saw my face could not believe the adverse reactions. Hopefully all the pre-cancerous cells are gone, was hoping to get rid of at least, some of the wrinkles as well after what I had been thru.
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jimb630

USA
4 Posts

Posted - 03/23/2014 :  14:33:23  Show Profile  Reply with Quote
I had to cover my entire forehead and temples to get many small spots, so I covered a lot of good skin. It all seemed to have about the same reaction (although not as bad as yours sounds), but it all healed up just fine. I had more scaling and crusting than I did blisters. The precancerous spots did react a little more than the normal skin.

Good luck!
Jim
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angbat

USA
2 Posts

Posted - 03/26/2014 :  10:41:08  Show Profile  Reply with Quote
Thank you, butkus22 and jimb630! I appreciate your responses. I called the Picato nurse line and the woman I spoke with said that what I was describing is a normal reaction. She also told me that I should not have any scarring. I don't look quite as freaky and hopefully, the skin reaction will just follow its course and do what it is supposed to do!

My dad uses Effudex and I might go that route if/when I have AK spots again as it sounds a little more mild.

Thanks again!
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Benoit

Canada
1 Posts

Posted - 04/06/2014 :  19:36:52  Show Profile  Reply with Quote
Today is April 6th,2014.
I started using Picato Gel on the 1rst, 2nd and third of April to the left side of my face below my eye. Was out raking the following 2 days. No discomfort, small amount of redness and peeling. Today is Sunday and the peeling is done and the redness is almost gone. Applying polysporin 4-6 x a day between rx's. Would I recommend it? Yes for me I've had no issues with it. Will see my dermatologist at the end of September 2014. All the best to everyone who needs to use it.
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Disclaimer: The three most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. While melanoma is the most dangerous type, keep in mind that any cancer can cause injury or death. The various views expressed in these public forums should not be considered as medical advice. See your qualified health-care professional for medical attention, advice, diagnosis, and treatments.