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dan
526 Posts |
 Posted - 09/09/2008 : 00:58:13
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The active ingredient in Curaderm and most probably the eggplant and apple cider vinegar skin cancer remedy was studied as a treatment for basal cell carcinoma as reported in the International Journal of Dermatology Volume 47 Issue 1, Pages 78 - 82 Published Online: 17 Dec 2007
Two topical treatments were compared in the study. The first (the control vehicle) was composed of the following: 15% emulsifying wax, 10% white soft paraffin, 10% salicylic acid (aspirin), 5% urea, and 5% propylene glycol. The other treatment called Zycure was composed of the vehicle plus 0.005% solasodine glycosides.
Results: Efficacy at 8 weeks was 66% (41/62) in the Zycure group, compared to 25% (8/32) in the control vehicle group. Ninety percent (37/41) of the Zycure group completed follow-up at six-month intervals for 1 year, of whom 78% (29/37) had no recurrence. There were no major treatment-related adverse effects, although 10 patients in Zycure group did not complete the treatment protocol for various reasons.
Conclusion: We conclude that the solasodine glycoside cream Zycure is a safe therapy for basal cell carcinoma, with a cure rate of 66% at 8 weeks.
Solasodine glycoalkaloids: a novel topical therapy for basal cell carcinoma. A double-blind, randomized, placebo-controlled, parallel group, multicenter study at http://www3.interscience.wiley.com/cgi-bin/fulltext/119389345/PDFSTART
see also http://www.townsendletter.com/AugSept2008/gabyeditorial0808.htm
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dan
526 Posts |
Posted - 09/10/2008 : 23:27:02
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There are several takeaways from this topical solasodine glycoalkaloids for skin cancer study.
The active ingredient in Curaderm and the eggplant and apple cider vinegar remedy is safe and quite often completely effective. However, enough people have commented that Curaderm (and for that matter the eggplant ACV remedy) did not work for them to doubt the claim that it was 100% effective against all skin cancers, and now we know better. Only about 50% had complete healing of their skin cancer after one year (29+/62). Plan on using it for at least eight weeks. Probably 12 weeks would have better results. If you are considering Curaderm this means about three $129 bottles according to the Townsend Letter link above. Eggplant ACV is much cheaper but very uncontrolled in terms of quality. If topical solasodine glycoalkaloids work for you, then great! If not, there are lots of other things to try.
Another interesting thing was the "control vehicle" was not exactly a placebo. Evidently aspirin and/or urea have some punch in them against skin cancer, and propylene glycol seems to be at least a safe if not helpful cosmetic ingredient for skin cancer when combining this study result with the recent moisturizer skin cancer study result. Most deodorants seem to use propylene glycol (AKA antifreeze) so maybe that is one less thing to worry about. |
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marsha
USA
122 Posts |
Posted - 09/11/2008 : 00:55:32
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| Dan are you saying that curaderm has antifreeze in it? |
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dan
526 Posts |
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Topical solasodine glycoalkaloids in 2007 study
